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Found 37 with Last Name = 'stokes' and Initial = 'ss'
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  7nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  18nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  23nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  58nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  280nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  400nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444676(CHEMBL1807815)
Affinity DataIC50:  430nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50:  2.10E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  3.30E+3nM Kd:  1.90E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  4.70E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  6.40E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444677(CHEMBL3098806)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50:  7.80E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444687(CHEMBL3098811)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444688(CHEMBL3098810)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  1.50E+4nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444685(CHEMBL3098813)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444684(CHEMBL3098814)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  4.00E+4nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444691(CHEMBL3098807)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444682(CHEMBL3098816)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444686(CHEMBL3098812)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444679(CHEMBL3098819)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444680(CHEMBL3098818)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444690(CHEMBL3098808)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444689(CHEMBL3098809)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444683(CHEMBL3098815)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444681(CHEMBL3098817)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50444678(CHEMBL3098820)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50335293((2R,3R,4S,5R)-2-(6-amino-2-(butylthio)-9H-purin-9-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human DNA Ligase I by FRET-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed