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Found 87 with Last Name = 'stokker' and Initial = 'ge'
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072639((S)-2-(2-{[(S)-2-((R)-2-Amino-3-mercapto-propylami...)
Affinity DataIC50:  0.123nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366557(CHEMBL1790748)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024972((+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-v...)
Affinity DataIC50:  5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024972((+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-v...)
Affinity DataIC50:  5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072626((S)-2-[2-({(S)-2-[2-(4-Cyano-benzylsulfanyl)-acety...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026169(6-[2-(5-Chloro-4'-fluoro-3,3'-dimethyl-biphenyl-2-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072647((S)-2-[2-({(S)-3-Methyl-2-[2-(4-nitro-benzylsulfan...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)
Affinity DataIC50:  7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)
Affinity DataIC50:  7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014669(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026164(6-[2-(3',4'-Dichloro-3,5-dimethyl-biphenyl-2-yl)-v...)
Affinity DataIC50:  8nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026149(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026148(6-[2-(3-Chloro-4'-fluoro-5,3'-dimethyl-biphenyl-2-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026167(6-[2-(3,5-Dichloro-3'-methyl-biphenyl-2-yl)-vinyl]...)
Affinity DataIC50:  13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026144(6-[2-(4'-Fluoro-3,5-dimethyl-biphenyl-2-yl)-vinyl]...)
Affinity DataIC50:  13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026152(6-[2-(3',4'-Dichloro-3,6-dimethyl-biphenyl-2-yl)-v...)
Affinity DataIC50:  13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072645((S)-2-[2-({(S)-3-Methyl-2-[2-(4-methyl-benzylsulfa...)
Affinity DataIC50:  14nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024974(4-Hydroxy-6-[2-(3,5,3'',5''-tetramethyl-biphenyl-2...)
Affinity DataIC50:  15nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024974(4-Hydroxy-6-[2-(3,5,3'',5''-tetramethyl-biphenyl-2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026158(6-[2-(3,5-Dichloro-3',5'-dimethyl-biphenyl-2-yl)-v...)
Affinity DataIC50:  16nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072633((S)-2-[2-({(S)-2-[2-(4-Methanesulfonyl-benzylsulfa...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072644((S)-2-[2-({(S)-2-[2-(4-Methoxy-benzylsulfanyl)-ace...)
Affinity DataIC50:  17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072628((S)-2-[2-({(S)-3-Methyl-2-[2-(pyridin-4-ylsulfanyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072623((S)-2-[2-({(S)-3-Methyl-2-[4-(4-nitro-phenyl)-buty...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026147(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-et...)
Affinity DataIC50:  22nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072629((S)-2-[2-({(S)-3-Methyl-2-[2-(3-nitro-benzylsulfan...)
Affinity DataIC50:  23nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024972((+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-v...)
Affinity DataIC50:  24nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026142(4-Hydroxy-6-[2-(3,5,3',4'-tetrachloro-biphenyl-2-y...)
Affinity DataIC50:  25nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072635((S)-2-[2-({(S)-2-[2-(Biphenyl-4-ylmethylsulfanyl)-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026163(6-[2-(3,5-Dichloro-4'-fluoro-3'-methyl-biphenyl-2-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026156(6-[2-(3-Chloro-4'-fluoro-3'-methyl-biphenyl-2-yl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072643((S)-2-[2-({(S)-2-[(1H-Imidazol-4-ylmethyl)-amino]-...)
Affinity DataIC50:  31nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072648((S)-2-(2-{[(S)-2-(2-Benzylsulfanyl-acetylamino)-3-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026168(4-Hydroxy-6-[2-(3,5,4'-trichloro-biphenyl-2-yl)-vi...)
Affinity DataIC50:  36nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026165(6-[2-(3,5-Dichloro-4'-fluoro-2'-methyl-biphenyl-2-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072649((S)-4-Methylsulfanyl-2-[2-({(S)-3-methyl-2-[2-(4-t...)
Affinity DataIC50:  37nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026141(4-Hydroxy-6-[2-(3,5,3',5'-tetrachloro-biphenyl-2-y...)
Affinity DataIC50:  37nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026146(6-[2-(3,5-Dichloro-3'-ethyl-biphenyl-2-yl)-vinyl]-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026150(6-[2-(4'-Fluoro-3'-hydroxymethyl-3,5-dimethyl-biph...)
Affinity DataIC50:  49nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026154(6-[2-(3,5-Dichloro-3'-methoxy-biphenyl-2-yl)-vinyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072627((S)-2-(2-{[(S)-3-Methyl-2-(2-phenylsulfanyl-acetyl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026143(6-[2-(3,5-Dichloro-3'-fluoro-biphenyl-2-yl)-vinyl]...)
Affinity DataIC50:  70nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072624((S)-2-[2-({(S)-2-[2-(Acetyl-benzyl-amino)-acetylam...)
Affinity DataIC50:  70nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024973(6-[2-(3,5-Dichloro-biphenyl-2-yl)-vinyl]-4-hydroxy...)
Affinity DataIC50:  80nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024973(6-[2-(3,5-Dichloro-biphenyl-2-yl)-vinyl]-4-hydroxy...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024977(6-(1,3-Dichloro-6-fluoro-9H-fluoren-9-ylmethyl)-4-...)
Affinity DataIC50:  85nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072641((S)-2-[2-({(S)-3-Methyl-2-[2-(2-nitro-benzylsulfan...)
Affinity DataIC50:  86nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026157(6-[2-(3,5-Dichloro-biphenyl-2-yl)-ethyl]-4-hydroxy...)
Affinity DataIC50:  100nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026166(6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vi...)
Affinity DataIC50:  106nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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