Compile Data Set for Download or QSAR
maximum 50k data
Found 15 with Last Name = 'straley' and Initial = 'ks'
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228659((+)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)
Affinity DataIC50:  30nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228658(rac-ML309)
Affinity DataIC50:  62nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228659((+)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)
Affinity DataIC50:  68nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228658(rac-ML309)
Affinity DataIC50:  96nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400269(CHEMBL2180730)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400268(CHEMBL2180740)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400267(CHEMBL2180746)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228660((-)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)
Affinity DataIC50:  1.50E+4nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400266(CHEMBL2180739)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400265(CHEMBL2180738)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228660((-)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)
Affinity DataIC50:  2.90E+4nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM228658(rac-ML309)
Affinity DataIC50:  3.60E+4nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400270(CHEMBL2180729)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400271(CHEMBL2180728)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type IDH1 using DL-isocitrate as substrate by resazurin-based fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed