Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human TBK1 using MBP as substrate in presence of gamma-33P]-ATP by Hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of TBK1 in human THP1 cells assessed as decrease in c-GAMP stimulated IFNbeta secretion preincubated for 45 mins followed by c-GAMP additi...More data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of TBK1 in TLR3-stimulated human PBMC assessed as decrease in poly(I:C)-induced IFNalpha secretion preincubated for 1 hr followed by poly(...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TBK1 in human Ramos cells assessed as decrease in poly(I:C)-stimulated IRF3 phosphorylation at Ser396 residue preincubated for 60 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of TBK1 in human THP1 cells assessed as decrease in baculovirus-stimulated IFNbeta secretion preincubated for 45 mins followed by virus ad...More data for this Ligand-Target Pair
Affinity DataKd: 158nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.01E+3nMAssay Description:Binding affinity to PI4KB in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by lipid-kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.94E+3nMAssay Description:Binding affinity to AAK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to IKKepsilon in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 631nMAssay Description:Binding affinity to ST17B in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 79nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 251nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 158nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair