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Found 207 with Last Name = 'sudbeck' and Initial = 'e'
TargetNeuraminidase(Influenza B virus (B/Lee/40))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM4707(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Affinity DataKi:  2.5nMAssay Description:In vitro inhibitory activity of the compound against B/Lee/40 Influenza B Neuraminidase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataKi:  600nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-phenyl)-et...)
Affinity DataKi:  600nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant HIV-1 Reverse transcriptase using cell free RT inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091963(1-(5-Bromo-pyridin-2-yl)-3-((R)-1-cyclohexyl-ethyl...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091962(1-(5-Chloro-pyridin-2-yl)-3-((R)-1-cyclohexyl-ethy...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091966(1-((R)-1-Cyclohexyl-ethyl)-3-thiazol-2-yl-thiourea...)
Affinity DataKi:  1.20E+4nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant HIV-1 Reverse transcriptase using cell free RT inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091971(1-((R)-1-Cyclohexyl-ethyl)-3-pyridin-2-yl-thiourea...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091964(1-((S)-1-Cyclohexyl-ethyl)-3-pyridin-2-yl-thiourea...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091972(1-(5-Bromo-pyridin-2-yl)-3-((S)-1-cyclohexyl-ethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091973(1-(5-Chloro-pyridin-2-yl)-3-((S)-1-cyclohexyl-ethy...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50091970(1-((S)-1-Cyclohexyl-ethyl)-3-thiazol-2-yl-thiourea...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Singapore/1/57(H2N2)))
University of Alabama At Birmingham

LigandPNGBDBM5266((2S,3S,4R)-4-carbamimidamido-2-(dipropylcarbamoyl)...)
Affinity DataIC50:  1nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM5265((2S,3S,4R)-4-carbamimidamido-3-acetamido-2-[(1R,2S...)
Affinity DataIC50:  4nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Singapore/1/57(H2N2)))
University of Alabama At Birmingham

LigandPNGBDBM5265((2S,3S,4R)-4-carbamimidamido-3-acetamido-2-[(1R,2S...)
Affinity DataIC50:  5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363465(CHEMBL1946646)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363455(CHEMBL1946333)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363466(CHEMBL1946647)
Affinity DataIC50:  11nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363455(CHEMBL1946333)
Affinity DataIC50:  12nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363465(CHEMBL1946646)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363462(CHEMBL1946340)
Affinity DataIC50:  14nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363466(CHEMBL1946647)
Affinity DataIC50:  16nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363462(CHEMBL1946340)
Affinity DataIC50:  17nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363464(CHEMBL1946495)
Affinity DataIC50:  22nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)
Affinity DataIC50:  24nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363464(CHEMBL1946495)
Affinity DataIC50:  24nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363467(CHEMBL1946837)
Affinity DataIC50:  25nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363456(CHEMBL1946334)
Affinity DataIC50:  26nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363456(CHEMBL1946334)
Affinity DataIC50:  31nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363454(CHEMBL1946332)
Affinity DataIC50:  46nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363450(CHEMBL1946328)
Affinity DataIC50:  46nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50078329(1-[4-CARBOXY-2-(3-PENTYLAMINO)PHENYL]-5,5'-DI(HYDR...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibitory activity of the compound against H1N9 Influenza A Neuraminidase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083680(1-(5-Bromo-pyridin-2-yl)-3-(2-thiophen-2-yl-ethyl)...)
Affinity DataIC50:  48nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363454(CHEMBL1946332)
Affinity DataIC50:  50nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)
Affinity DataIC50:  52nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363463(CHEMBL1946341)
Affinity DataIC50:  63nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50:  66nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50097041(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50:  70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363455(CHEMBL1946333)
Affinity DataIC50:  75nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363458(CHEMBL1946336)
Affinity DataIC50:  83nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363465(CHEMBL1946646)
Affinity DataIC50:  91nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363458(CHEMBL1946336)
Affinity DataIC50:  96nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50206060(1-(2,5-dimethoxyphenethyl)-3-(5-bromopyridin-2-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50206060(1-(2,5-dimethoxyphenethyl)-3-(5-bromopyridin-2-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50:  110nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363447(CHEMBL1946325)
Affinity DataIC50:  120nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363449(CHEMBL1946327)
Affinity DataIC50:  130nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363450(CHEMBL1946328)
Affinity DataIC50:  130nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363459(CHEMBL1946337)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363452(CHEMBL1946330)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363449(CHEMBL1946327)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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