Affinity DataIC50: 0.140nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant SPT2 activity in LCB2 transfected human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant SPT1 activity in LCB1 transfected human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 12.4nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair