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Found 207 with Last Name = 'sundaram' and Initial = 'a'
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554031(CHEMBL4749110)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554030(CHEMBL4756339)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554033(CHEMBL4794201)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554032(CHEMBL4741135)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199195(CHEMBL3892042 | US10131658, Compound 8)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554033(CHEMBL4794201)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of alpha5beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472679(US10836720, HIJ-1017)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of alpha5beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554032(CHEMBL4741135)
Affinity DataIC50:  1nMAssay Description:Inhibition of alpha5beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554031(CHEMBL4749110)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of alpha5beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554030(CHEMBL4756339)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of alpha5beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of alpha5beta1 integrin in human SW480 cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mins by crystal viole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50:  4nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50:  31nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472689(US10836720, HIJ-1094)
Affinity DataIC50:  32nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472698(US10836720, HIJ-1437)
Affinity DataIC50:  32nMAssay Description:Inhibition of alpha5beta1 integrin in human SW480 cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mins by crystal viole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472689(US10836720, HIJ-1094)
Affinity DataIC50:  40nMAssay Description:Inhibition of alpha5beta1 integrin in human SW480 cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mins by crystal viole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50:  49nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472690(US10836720, HIJ-1099)
Affinity DataIC50:  50nMAssay Description:Inhibition of alpha5beta1 integrin in human SW480 cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mins by crystal viole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50:  51nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50:  59nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50262462((S)-2-(3-(benzo[b]thiophen-3-ylmethyl)morpholino)-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50:  63nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50:  74nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585090(US11530180, Compound SU15210-0230-01)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472698(US10836720, HIJ-1437)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472692(US10836720, HIJ-1204)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472690(US10836720, HIJ-1099)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472689(US10836720, HIJ-1094)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472689(US10836720, HIJ-1094)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472679(US10836720, HIJ-1017)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585097((S)-2-(2,6-dichloro-4-(1H-indazol-6-yl)benzamido)-...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585096((S)-2-(2,6-dichloro-4-morpholinobenzamido)-3-(2-(3...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585094((benzyl (2 S)-2-[[2,6-dichloro-4-(1,1-di oxo-1,4-t...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585093((2S)-2-(2,6-dichloro-4-morpholinobenzamido)-3-(2-(...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585092((2S)-2-(2,6-dichloro-4-(1H-indazol-6-yl)benzamido)...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585091(US11530180, Compound SU15210-0238-01)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50554031(CHEMBL4749110)
Affinity DataIC50:  100nMAssay Description:Inhibition of alpha4beta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM584980(US11530180, Compound Table 1.1)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM584989(US11530180, Compound Table 1.2 | US11530180, Compo...)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585011(US11530180, Compound Table 1.3)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM585038(US11530180, Compound Table 1.4)
Affinity DataIC50: <100nMAssay Description:Evaluation of cell attachment to extracellular matrix proteins was performed as previously described by Yokosaki et al, J. Biol. Chem., 271: (39): 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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