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Found 52 with Last Name = 'surina' and Initial = 'e'
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50052398((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid |...)
Affinity DataEC50:  200nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.32E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  610nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50069348((S)-2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 6 stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50069349((S)-2-Amino-2-benzyl-3-(3,5-dioxo-[1,2,4]oxadiazol...)
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 4a stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50069348((S)-2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 4a stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50069349((S)-2-Amino-2-benzyl-3-(3,5-dioxo-[1,2,4]oxadiazol...)
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 6 stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  5.10nMAssay Description:Compound was evaluated for agonist activity against human mGluR2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50052398((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid |...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing chimeric mGluR3/1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing chimeric mGluR3/1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50078596((2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic a...)
Affinity DataEC50:  5.20E+4nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing chimeric mGluR3/1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing chimeric mGluR3/1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  3.10E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  3.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  3.80E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  1.30E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.40E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  290nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  5.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.30E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.20E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.50E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  9.10E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  9.80E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.21E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  5.10nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.70E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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