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Found 536 with Last Name = 'surman' and Initial = 'md'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50184924(1-((1S,2R,5S)-5-(4-cyanophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331198(1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331161(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331161(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331199(4-(4-methoxyphenyl)-1-(5-methyl-2,3,4,5-tetrahydro...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331161(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331201(4-(4-chlorophenyl)-1-(5-methyl-2,3,4,5-tetrahydro-...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331172(4-(2-chloro-4-methoxyphenyl)-1-(1-(2-(pyrrolidin-1...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331251((R)-4-(benzyloxy)-1-(1-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331170(4-(2,4-dichlorophenyl)-1-(1-(2-(pyrrolidin-1-yl)et...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331212(4-(benzyloxy)-1-(2-(2-hydroxyethyl)-5-methyl-2,3,4...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331187(4-(benzyloxy)-1-(2,3,4,5-tetrahydro-1H-pyrido[4,3-...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331174(4-(2-methyl-4-(trifluoromethoxy)phenyl)-1-(1-(2-(p...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331200(1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331242(2-(4-chloro-2-fluorophenyl)-5-(1-(2-(pyrrolidin-1-...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331209(4-(4-chlorobenzyloxy)-1-(5-methyl-2,3,4,5-tetrahyd...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331186(4-(benzyloxy)-1-(2,5-dimethyl-2,3,4,5-tetrahydro-1...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113660(US8637501, 64)
Affinity DataKi:  4.60nM ΔG°:  -47.6kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113617(US8637501, 21)
Affinity DataKi:  4.70nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM153245(US8993765, 10)
Affinity DataKi:  4.70nMpH: 7.4Assay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331245(4-(benzyloxy)-1-(1-(2-(dimethylamino)ethyl)-1H-ind...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113619(US8637501, 23)
Affinity DataKi:  4.70nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113628(US8637501, 32)
Affinity DataKi:  4.90nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113625(US8637501, 29)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113626(US8637501, 30)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113659(US8637501, 63)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331168(1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331236(2-(4-chlorophenyl)-5-(1-(2-(pyrrolidin-1-yl)ethyl)...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331184(4-(benzyloxy)-1-(2,9-dimethyl-2,3,4,9-tetrahydro-1...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113623(US8637501, 27)
Affinity DataKi:  5.30nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM112722(US8629158, 36)
Affinity DataKi:  5.30nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331196(4-(4-chlorophenyl)-1-(2,9-dimethyl-2,3,4,9-tetrahy...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331171(4-(2-chloro-4-(trifluoromethyl)phenyl)-1-(1-(2-(py...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113631(US8637501, 35)
Affinity DataKi:  5.80nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113709(US8637501, 113)
Affinity DataKi:  5.90nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM167874(US9073925, 3)
Affinity DataKi:  5.90nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113603(US8637501, 7)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM109806(US8618299, 24)
Affinity DataKi:  6nMAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113699(US8637501, 103)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331239(2-(4-fluorophenyl)-5-(1-(2-(pyrrolidin-1-yl)ethyl)...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113622(US8637501, 26)
Affinity DataKi:  6.10nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113620(US8637501, 24)
Affinity DataKi:  6.40nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113686(US8637501, 90)
Affinity DataKi:  6.40nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM167873(US9073925, 2)
Affinity DataKi:  6.40nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM112692(US8629158, 5)
Affinity DataKi:  6.5nM ΔG°:  -46.7kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50331210(1-(5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]ind...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM113683(US8637501, 87)
Affinity DataKi:  6.90nM ΔG°:  -46.6kJ/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In DepthDetails US Patent
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