Affinity DataIC50: 0.670nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 904nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair