Found 395 with Last Name = 'svensson' and Initial = 'f' TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Iota Pharmaceuticals
Curated by ChEMBL
Iota Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of N-terminal 6xHis-tagged PDE10A (unknown origin) expressed in BL21 (DE3) RIL cells using 3',5'-cGMP as substrate by microcalorimetric as...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human Notum using OPTS substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human Notum using OPTS substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of C-terminal His-tagged Notum (Ser81-Thr451 Cys330Ser) (unknown origin) using OPTS as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notum using OPTS substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
