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Found 263 with Last Name = 'svenstrup' and Initial = 'n'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM97722(US8476267, 19)
Affinity DataIC50:  3nMT: 2°CAssay Description:The inhibitory activity of active substance is determined in a biochemical assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM97723(US8476267, 24)
Affinity DataIC50:  5nMT: 2°CAssay Description:The inhibitory activity of active substance is determined in a biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247218(US9434733, methyl 5-[[3-methyl-4-(4-oxo-7-tetrahyd...)
Affinity DataIC50:  8nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247218(US9434733, methyl 5-[[3-methyl-4-(4-oxo-7-tetrahyd...)
Affinity DataIC50:  8nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM97721(US8476267, 17)
Affinity DataIC50:  8nMT: 2°CAssay Description:The inhibitory activity of active substance is determined in a biochemical assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247218(US9434733, methyl 5-[[3-methyl-4-(4-oxo-7-tetrahyd...)
Affinity DataIC50:  8nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM559571(US11370795, Compound (P3)
Affinity DataIC50:  10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM559572(US11370795, Compound (P4))
Affinity DataIC50:  10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247177(US9434733, 2-[4-methyl-1-[[4-(trifluoromethyl)phen...)
Affinity DataIC50:  12nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247177(US9434733, 2-[4-methyl-1-[[4-(trifluoromethyl)phen...)
Affinity DataIC50:  12nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247177(US9434733, 2-[4-methyl-1-[[4-(trifluoromethyl)phen...)
Affinity DataIC50:  12nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247225(US9434733, 2-[1-[(5-chloro-2-thienyl)methyl]-4-met...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247192(US9434733, 2-[1-[[4-(diethylamino)phenyl]methyl]-4...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247192(US9434733, 2-[1-[[4-(diethylamino)phenyl]methyl]-4...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247192(US9434733, 2-[1-[[4-(diethylamino)phenyl]methyl]-4...)
Affinity DataIC50:  13nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247225(US9434733, 2-[1-[(5-chloro-2-thienyl)methyl]-4-met...)
Affinity DataIC50:  13nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247225(US9434733, 2-[1-[(5-chloro-2-thienyl)methyl]-4-met...)
Affinity DataIC50:  13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM97717(US8476267, 2)
Affinity DataIC50:  16nMT: 2°CAssay Description:The inhibitory activity of active substance is determined in a biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247183(US9434733, 2-[4-methyl-1-[[4-(trifluoromethoxy)phe...)
Affinity DataIC50:  19nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247183(US9434733, 2-[4-methyl-1-[[4-(trifluoromethoxy)phe...)
Affinity DataIC50:  19nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247183(US9434733, 2-[4-methyl-1-[[4-(trifluoromethoxy)phe...)
Affinity DataIC50:  19nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247195(US9434733, 2-[1-[(2-chloro-4-fluoro-phenyl)methyl]...)
Affinity DataIC50:  21nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247195(US9434733, 2-[1-[(2-chloro-4-fluoro-phenyl)methyl]...)
Affinity DataIC50:  21nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247195(US9434733, 2-[1-[(2-chloro-4-fluoro-phenyl)methyl]...)
Affinity DataIC50:  21nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM97718(US8476267, 4)
Affinity DataIC50:  21nMT: 2°CAssay Description:The inhibitory activity of active substance is determined in a biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247222(US9434733, 2-[(1R)-1-[3-(4-methoxyphenyl)azetidin-...)
Affinity DataIC50:  22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247224(US9434733, 2-[4-methyl-1-[(5-methyl-2-thienyl)meth...)
Affinity DataIC50:  22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247224(US9434733, 2-[4-methyl-1-[(5-methyl-2-thienyl)meth...)
Affinity DataIC50:  22nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247224(US9434733, 2-[4-methyl-1-[(5-methyl-2-thienyl)meth...)
Affinity DataIC50:  22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247222(US9434733, 2-[(1R)-1-[3-(4-methoxyphenyl)azetidin-...)
Affinity DataIC50:  22nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247222(US9434733, 2-[(1R)-1-[3-(4-methoxyphenyl)azetidin-...)
Affinity DataIC50:  22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247215(US9434733, 2-[1-[(3,4-difluorophenyl)methyl]-4-met...)
Affinity DataIC50:  23nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247215(US9434733, 2-[1-[(3,4-difluorophenyl)methyl]-4-met...)
Affinity DataIC50:  23nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247215(US9434733, 2-[1-[(3,4-difluorophenyl)methyl]-4-met...)
Affinity DataIC50:  23nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247186(US9434733, 2-[4-methyl-1-(quinoxalin-6-ylmethyl)py...)
Affinity DataIC50:  24nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247186(US9434733, 2-[4-methyl-1-(quinoxalin-6-ylmethyl)py...)
Affinity DataIC50:  24nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247186(US9434733, 2-[4-methyl-1-(quinoxalin-6-ylmethyl)py...)
Affinity DataIC50:  24nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247213(US9434733, 2-[1-[(5-fluoro-3-pyridyl)methyl]-4-met...)
Affinity DataIC50:  25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247193(US9434733, 2-[1-(2-furylmethyl)-4-methyl-pyrrolidi...)
Affinity DataIC50:  25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247193(US9434733, 2-[1-(2-furylmethyl)-4-methyl-pyrrolidi...)
Affinity DataIC50:  25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247193(US9434733, 2-[1-(2-furylmethyl)-4-methyl-pyrrolidi...)
Affinity DataIC50:  25nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247213(US9434733, 2-[1-[(5-fluoro-3-pyridyl)methyl]-4-met...)
Affinity DataIC50:  25nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247213(US9434733, 2-[1-[(5-fluoro-3-pyridyl)methyl]-4-met...)
Affinity DataIC50:  25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247196(US9434733, 2-[1-[(4-dimethylaminophenyl)methyl]-4-...)
Affinity DataIC50:  27nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM247196(US9434733, 2-[1-[(4-dimethylaminophenyl)methyl]-4-...)
Affinity DataIC50:  27nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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