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Found 31 with Last Name = 'swamy' and Initial = 'n'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50:  300nMAssay Description:Inhibition of NNMT in human U2OS cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50:  512nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455085(CHEMBL4217817)
Affinity DataIC50:  580nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455092(CHEMBL4218043)
Affinity DataIC50:  588nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455087(CHEMBL4207500)
Affinity DataIC50:  922nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Mus musculus)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of NNMT in mouse 3T3L1 cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Mus musculus)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of mouse NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455086(CHEMBL4204179)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50340090(4-methoxybenzamide | CHEMBL449635)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455081(CHEMBL4209724)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455097(CHEMBL4205858)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455080(CHEMBL4207893)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455082(CHEMBL4215561)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455094(CHEMBL4212164)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455079(CHEMBL4210945)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM228815(5-MeO-PZA)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455088(CHEMBL4206735)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455089(CHEMBL4209022)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455090(CHEMBL4202617)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455091(CHEMBL4216237)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455077(CHEMBL1997189)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455093(CHEBI:27410 | CHEMBL3542314)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455084(CHEMBL4214098)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50455083(CHEMBL4218838)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Boston University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50217045(CHEMBL2068062)
Affinity DataEC50:  274nMAssay Description:Displacement of [3H]estradiol from estrogen receptor-ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Boston University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  1nMAssay Description:Displacement of [3H]estradiol from estrogen receptor-ligand binding domainMore data for this Ligand-Target Pair