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Found 56 with Last Name = 'swanson' and Initial = 'sm'
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)
Affinity DataIC50:  75nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)
Affinity DataIC50:  75nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)
Affinity DataIC50:  80nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)
Affinity DataIC50:  250nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513777(CHEMBL4534212)
Affinity DataIC50:  600nMAssay Description:Inhibition of Papaya papain using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50347543(CHEMBL1801948)
Affinity DataIC50:  750nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513779(CHEMBL4441556)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346334(1,3,7-trihydroxy-2,4-diisoprenylxanthone | CHEMBL1...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346333((1S,3aR,5R,12aR)-3,3a,4,5-tetrahydro-8,10-dihydrox...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli assessed as reduction in p-nitrophenol formation using p-nitr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50241454(1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513778(CHEMBL4470415)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346339(4-Methyl-3,6-di-O-methyl-alpha-mangostin | CHEMBL1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346340(3,6-di-O-methyl-alpha-mangostin | CHEMBL464524 | d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346341(6-O-benzoyl-alpha-mangostin | CHEMBL1782245)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346342(1-isomangostin hydrate | CHEMBL1782247)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346343(3,7-Di-O-acetylcochinchinone A | CHEMBL1782248)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346337(3,6-di-O-acetyl-alpha-mangostin | CHEMBL465553 | d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346345(3,7-Di-O-methylcochinchinone A | CHEMBL1782583)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346346(7-O-Benzoylcochinchinone A | CHEMBL1782584)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346344(7-O-Methylcochinchinone A | CHEMBL1782582)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346336(3-O-acetyl-alpha-mangostin | CHEMBL1782242)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346335(CHEMBL1782241 | Cochinchinone A)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346338(7-methoxy-2,8-bis(3-methylbut-2-enyl)-9-oxo-9H-xan...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50346333((1S,3aR,5R,12aR)-3,3a,4,5-tetrahydro-8,10-dihydrox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM241952(Fukugetin)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of Papaya papain using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311742(8-DEOXYGARTANIN | 8-desoxygartanin | CHEMBL488606)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50241454(1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513779(CHEMBL4441556)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of Papaya papain using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513778(CHEMBL4470415)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of Papaya papain using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50513778(CHEMBL4470415)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of trypsin (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311745(11-hydroxy-3-O-methyl-1-isomangostin | CHEMBL10806...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311744(CHEMBL1076209 | cratoxyxanthone)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311740(11-hydroxy-1-isomangostin | CHEMBL1080697)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311741(1,6-dihydroxy-7-methoxy-8-(3-methylbut-2-enyl)-6',...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311744(CHEMBL1076209 | cratoxyxanthone)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311745(11-hydroxy-3-O-methyl-1-isomangostin | CHEMBL10806...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311740(11-hydroxy-1-isomangostin | CHEMBL1080697)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311741(1,6-dihydroxy-7-methoxy-8-(3-methylbut-2-enyl)-6',...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311742(8-DEOXYGARTANIN | 8-desoxygartanin | CHEMBL488606)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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