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Found 13 with Last Name = 'swarbrick' and Initial = 'jm'
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027369(CHEMBL3342444)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027370(CHEMBL3342440)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446561(CHEMBL3110215)
Affinity DataIC50:  1.10E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027374(CHEMBL3342443)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027373(CHEMBL3342442)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446559(CHEMBL3110213)
Affinity DataIC50:  4.90E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446560(CHEMBL3110214)
Affinity DataIC50:  5.10E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446558(CHEMBL3110195)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446557(CHEMBL3110204)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50324670(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027372(CHEMBL3342441)
Affinity DataIC50:  1.58E+5nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50027371(CHEMBL1161863 | Cyclic Inosine 5''-Diphosphoribose)
Affinity DataIC50:  2.76E+5nMAssay Description:Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446562(CHEMBL3110216)
Affinity DataIC50:  3.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed