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Found 24 with Last Name = 'sweeny' and Initial = 'dj'
LigandPNGBDBM50286012(3-{(R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of platelet activating factor(PAF) by binding to PAF receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50035397(6-(4-Fluoro-phenyl)-3-((R)-3-pyridin-3-yl-1H-pyrro...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of platelet activating factor (PAF) by binding to PAF receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286013((cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-p...)
Affinity DataKi:  68nMAssay Description:Inhibition of platelet activating factor(PAF) by binding to PAF receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286013((cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-p...)
Affinity DataKi:  68nMAssay Description:Inhibition of platelet activating factor(PAF) by binding to PAF receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Gilead Sciences

LigandPNGBDBM4994((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)
Affinity DataIC50:  1nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Gilead Sciences

LigandPNGBDBM4994((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)
Affinity DataIC50:  4nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Gilead Sciences

LigandPNGBDBM5248((3R,4R,5S)-5-amino-4-acetamido-3-{[(3R)-1-hydroxyp...)
Affinity DataIC50:  30nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Gilead Sciences

LigandPNGBDBM5249((3R,4R,5S)-5-amino-4-acetamido-3-{[(3S)-1-hydroxyp...)
Affinity DataIC50:  40nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Gilead Sciences

LigandPNGBDBM5248((3R,4R,5S)-5-amino-4-acetamido-3-{[(3R)-1-hydroxyp...)
Affinity DataIC50:  85nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Gilead Sciences

LigandPNGBDBM5249((3R,4R,5S)-5-amino-4-acetamido-3-{[(3S)-1-hydroxyp...)
Affinity DataIC50:  400nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Gilead Sciences

LigandPNGBDBM5246((3R,4R,5S)-5-amino-3-{[(2R)-1-carboxybutan-2-yl]ox...)
Affinity DataIC50:  450nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Gilead Sciences

LigandPNGBDBM5247((3R,4R,5S)-5-amino-3-{[(2S)-1-carboxybutan-2-yl]ox...)
Affinity DataIC50:  1.15E+3nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM327998(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- cya...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328001(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(fluoro...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328133(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(2,4- d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328006(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328171(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328133(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(2,4- d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328171(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM328006(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM327927(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4-fluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM327927(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4-fluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed