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Found 188 with Last Name = 'szajnman' and Initial = 'sh'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25298((1-hydroxy-1-phosphonoheptyl)phosphonic acid | CHE...)
Affinity DataKi:  240nMAssay Description:Inhibitory concentration of the compound against Trypanosoma brucei farnesyl pyrophosphate synthase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132606((1-Phosphono-nonyl)-phosphonic acid | CHEMBL111695)
Affinity DataKi:  310nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25298((1-hydroxy-1-phosphonoheptyl)phosphonic acid | CHE...)
Affinity DataKi:  400nMAssay Description:Inhibition of trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097889((1-Hydroxy-1-phosphono-hexyl)-phosphonic acid | 1-...)
Affinity DataKi:  400nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25298((1-hydroxy-1-phosphonoheptyl)phosphonic acid | CHE...)
Affinity DataKi:  400nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132608((1-Phosphono-hexyl)-phosphonic acid | CHEMBL280463)
Affinity DataKi:  470nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132600((1-Phosphono-heptyl)-phosphonic acid | CHEMBL32208...)
Affinity DataKi:  540nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataKi:  590nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132602((1-Phosphono-pentyl)-phosphonic acid | CHEMBL32255...)
Affinity DataKi:  790nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097886((1-Hydroxy-1-phosphono-octyl)-phosphonic acid | 1-...)
Affinity DataKi:  980nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132605((1-Phosphono-octyl)-phosphonic acid | CHEMBL324003)
Affinity DataKi:  1.88E+3nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataKi:  5.04E+3nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50132599((1-Phosphono-butyl)-phosphonic acid | CHEMBL112840)
Affinity DataKi:  1.70E+4nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426981(CHEMBL2326236)
Affinity DataIC50:  9nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374762(CHEMBL261432)
Affinity DataIC50:  13nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50:  13nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50:  13nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426982(CHEMBL2326237)
Affinity DataIC50:  16nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50:  21nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50:  21nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426975(CHEMBL2326230)
Affinity DataIC50:  24nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426976(CHEMBL2326231)
Affinity DataIC50:  25nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521859(CHEMBL4460779)
Affinity DataIC50:  34nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444839(CHEMBL3099275)
Affinity DataIC50:  35nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444839(CHEMBL3099275)
Affinity DataIC50:  35nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374757(CHEMBL408745)
Affinity DataIC50:  38nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444843(CHEMBL3099279)
Affinity DataIC50:  39nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444843(CHEMBL3099279)
Affinity DataIC50:  39nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426990(CHEMBL2326226)
Affinity DataIC50:  48nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521859(CHEMBL4460779)
Affinity DataIC50:  51nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444842(CHEMBL3099278)
Affinity DataIC50:  51nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426983(CHEMBL2326238)
Affinity DataIC50:  56nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444844(CHEMBL3099276)
Affinity DataIC50:  60nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521851(CHEMBL4540565)
Affinity DataIC50:  60nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444844(CHEMBL3099276)
Affinity DataIC50:  60nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426989(CHEMBL2096957)
Affinity DataIC50:  66nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444841(CHEMBL3099277)
Affinity DataIC50:  67nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426974(CHEMBL2326229)
Affinity DataIC50:  69nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426974(CHEMBL2326229)
Affinity DataIC50:  69nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521853(CHEMBL4464077)
Affinity DataIC50:  71nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Toxoplasma gondii recombinant FPPS expressed in Escherichia coli using [4-14C]IPP/DMAPP/GPP as substrate after 30 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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