Compile Data Set for Download or QSAR
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Found 66 with Last Name = 'szymanski' and Initial = 'am'
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50:  800nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  1.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50:  1.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  2.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  3.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)
Affinity DataIC50:  4.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24550(3-{2-[(3Z)-5-{[(3-chloro-4-fluorophenyl)methyl]sul...)
Affinity DataIC50:  4.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)
Affinity DataIC50:  5.20E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  5.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  5.90E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  6.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  7.10E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  7.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  7.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  8.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  9.30E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)
Affinity DataIC50:  9.80E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  1.06E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.08E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.13E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.14E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.17E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24538((3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo...)
Affinity DataIC50:  1.19E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.45E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50:  1.54E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.54E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  1.57E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50:  1.58E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.59E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.80E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.81E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.83E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.88E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)
Affinity DataIC50:  1.93E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  1.94E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)
Affinity DataIC50:  1.94E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)
Affinity DataIC50:  2.23E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  2.29E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  2.57E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  2.77E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  3.24E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50:  3.26E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  3.28E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50:  3.71E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50:  3.82E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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