Affinity DataKi: 0.0251nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:In vitro functional activity towards Neurokinin NK2 receptor on isolated rabbit urinary bladder (RUB)More data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:In vitro functional activity towards Neurokinin NK2 receptor on isolated rabbit urinary bladder (RUB)More data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0525nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0575nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0603nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0759nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0977nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory affinity constant (pKi) against tachykinin receptor 2 (NK-2R) using heterologous competition experimentsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.115nMAssay Description:Binding affinity to wild type A3R (unknown origin) expressed in CHO-K1 cells assessed as equilibrium binding affinity constant by nanoBRET assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.115nMAssay Description:Displacement of CA200645 from NLuc human A3 receptor expressed in HEK293 cells assessed as inhibition constant by NanoBRET binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro functional activity towards Neurokinin NK2 receptor on isolated rabbit urinary bladder (RUB)More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.132nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Inhibitory affinity constant (pKi) against tachykinin receptor 2 (NK-2R) using heterologous competition experimentsMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/mole EC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.234nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.234nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair