Affinity DataKi: 0.0501nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.135nMAssay Description:Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.178nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.288nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.295nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.302nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity to human 5HT2C receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.331nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.372nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.562nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.575nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.603nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.646nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.661nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.708nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type B receptor of guinea pigMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.724nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.724nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.759nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Binding affinity to human 5HT2C receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Binding affinity to human 5HT2C receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.832nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.851nMAssay Description:Displacement of [3H]citalopram from mouse cortex SERT by filtration binding assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.933nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.955nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.955nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.977nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair