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Found 47 with Last Name = 'thomason' and Initial = 'da'
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291312(4-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  2nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  6nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291315(5-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  8nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291311(6-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  20nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291316(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  20nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi:  43nMAssay Description:Tested for its inhibitory activity against human microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291317(CHEMBL154472 | [3-Allyl-4-(3-hydroxy-1-aza-bicyclo...)
Affinity DataKi:  100nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291314(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291319(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291318(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291313(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50047126(2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50:  5nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283596(1-[4-(2-Ethyl-5,6,7,8-tetrahydro-quinolin-4-yloxym...)
Affinity DataIC50:  6nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283591(4-[2-Chloro-2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  7nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283597(2-Ethyl-4-[2-methoxy-2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283587(2-Ethyl-4-[3-fluoro-2'-(2H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  9nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283593(4-(2-Ethyl-5,6,7,8-tetrahydro-quinolin-4-yloxymeth...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283590(4-(2-Ethyl-5,6,7,8-tetrahydro-quinolin-4-yloxymeth...)
Affinity DataIC50:  27nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283589(2-Ethyl-4-[2'-methyl-6'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  29nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283592(2-Ethyl-4-[4'-methyl-2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  54nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283595(2-Ethyl-4-[5'-methoxy-2'-(2H-tetrazol-5-yl)-biphen...)
Affinity DataIC50:  67nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283588(4-[4'-Chloro-2'-(2H-tetrazol-5-yl)-biphenyl-4-ylme...)
Affinity DataIC50:  93nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50005340(2-Butyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50:  96nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50283594(2-Ethyl-4-[4'-methoxy-2'-(2H-tetrazol-5-yl)-biphen...)
Affinity DataIC50:  140nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  480nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230428(CHEMBL352376)
Affinity DataIC50:  640nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230436(CHEMBL424372)
Affinity DataIC50:  860nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230438(CHEMBL171530)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230431(CHEMBL171456)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230439(CHEMBL172344)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50005347(4'-((2-butyl-1H-benzo[d]imidazol-1-yl)methyl)biphe...)
Affinity DataIC50:  2.30E+3nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230427(CHEMBL171490)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230440(CHEMBL171395)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230435(CHEMBL172577)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230434(CHEMBL172056)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230424(CHEMBL558388)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230429(CHEMBL354435)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230425(CHEMBL355691)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230426(CHEMBL367565)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230441(CHEMBL171681)
Affinity DataIC50:  9.40E+3nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230539(CHEMBL172334)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230437(CHEMBL367566)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230430(CHEMBL354436)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230432(CHEMBL171317)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230423(CHEMBL171875)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50230433(CHEMBL422562)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed