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Found 47 with Last Name = 'torrence' and Initial = 'pf'
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022238((R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphat...)
Affinity DataKi:  14nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010241(CHEMBL1234672)
Affinity DataKi:  29nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010236(CHEMBL3144200)
Affinity DataKi:  39nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50000038(CHEMBL3228321)
Affinity DataKi:  40nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010239(CHEMBL1236538)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010240(CHEMBL3246102)
Affinity DataKi:  550nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010238(CHEMBL1160593)
Affinity DataKi:  1.40E+3nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010242(CHEMBL1160594)
Affinity DataKi:  1.60E+3nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085553(CHEMBL214603 | Oligoadenylate analogue)
Affinity DataIC50:  0.720nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50:  0.950nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in human Daudi lymphoblastoid cellsMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025002(CHEMBL404038 | ppp'A2'p5'A2'p5'A | ppp5'A2'p5'A2'p...)
Affinity DataIC50:  2.30nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085558(CHEMBL402676 | Oligoadenylate analogue)
Affinity DataIC50:  2.60nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataIC50:  7.30nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50:  13nMAssay Description:Displacement of the probe bound to Ribonuclease L by compound in radiobinding assay was evaluatedMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in rabbit reticulocytesMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085556(CHEMBL405496 | Oligoadenylate analogue)
Affinity DataIC50:  24nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025005(CHEMBL3143469 | pp5'(br8A)2'p5'(br8A)2'p5'(br8A))
Affinity DataIC50:  48nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085555(CHEMBL384725 | Oligoadenylate analogue)
Affinity DataIC50:  57nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085559(CHEMBL410213 | Oligoadenylate analogue)
Affinity DataIC50:  105nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025001(CHEMBL3143411 | pp5'(br8A)2'p5'(br8A)2'p5'(br8A)2'...)
Affinity DataIC50:  150nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50021104((2'-5'(pAris)3)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in human Daudi lymphoblastoid cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025000(CHEMBL3143409 | ppp5'(br8A)2'p5'(br8A)2'p5'(br8A))
Affinity DataIC50:  250nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021104((2'-5'(pAris)3)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024997(CHEMBL3143462 | p5'(br8A)2'p5'(br8A)2'p5'(br8A))
Affinity DataIC50:  700nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025003((br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL3143413)
Affinity DataIC50:  1.00E+3nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataIC50:  1.06E+3nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50021104((2'-5'(pAris)3)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in rabbit reticulocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025006((br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL31...)
Affinity DataIC50: >4.00E+4nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025004(CHEMBL3143467 | p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p...)
Affinity DataIC50: >5.00E+4nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024999(CHEMBL414948 | Sulfuric acid mono-{5-(6-amino-puri...)
Affinity DataIC50:  2.00E+5nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024998(CHEMBL3143412 | p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p...)
Affinity DataIC50: >2.00E+5nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085558(CHEMBL402676 | Oligoadenylate analogue)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085555(CHEMBL384725 | Oligoadenylate analogue)
Affinity DataEC50:  0.840nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.150nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085559(CHEMBL410213 | Oligoadenylate analogue)
Affinity DataEC50:  4nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085556(CHEMBL405496 | Oligoadenylate analogue)
Affinity DataEC50:  0.800nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085559(CHEMBL410213 | Oligoadenylate analogue)
Affinity DataEC50:  4.60nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085555(CHEMBL384725 | Oligoadenylate analogue)
Affinity DataEC50:  0.700nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085556(CHEMBL405496 | Oligoadenylate analogue)
Affinity DataEC50:  0.680nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  16nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  30nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataEC50:  0.210nMAssay Description:Binding affinity of compound to human recombinant Ribonuclease L was evaluatedMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085553(CHEMBL214603 | Oligoadenylate analogue)
Affinity DataEC50:  0.240nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085558(CHEMBL402676 | Oligoadenylate analogue)
Affinity DataEC50:  0.130nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085553(CHEMBL214603 | Oligoadenylate analogue)
Affinity DataEC50:  0.300nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed