Compile Data Set for Download or QSAR
maximum 50k data
Found 147 with Last Name = 'trout' and Initial = 're'
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19769((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)
Affinity DataKi:  0.160nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.260nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002402(CHEMBL194643)
Affinity DataKi:  0.430nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.470nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002399(CHEMBL197958)
Affinity DataKi:  0.560nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002374(CHEMBL194861)
Affinity DataKi:  0.570nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19808(benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl...)
Affinity DataKi:  0.600nM ΔG°:  -52.1kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.740nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002399(CHEMBL197958)
Affinity DataKi:  0.870nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002366(CHEMBL433985)
Affinity DataKi:  0.890nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002400(CHEMBL382286)
Affinity DataKi:  1.40nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19813(benzyl N-[(2S)-4-methyl-1-{3-[(2S)-4-methyl-2-(qui...)
Affinity DataKi:  1.60nM ΔG°:  -49.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002367(CHEMBL407633)
Affinity DataKi:  1.70nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19811(benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl...)
Affinity DataKi:  1.90nM ΔG°:  -49.3kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002399(CHEMBL197958)
Affinity DataKi:  2nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19769((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)
Affinity DataKi:  2.20nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19807(CHEMBL100563 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  2.30nM ΔG°:  -48.8kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19810(CHEMBL118449 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  2.60nM ΔG°:  -48.5kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002374(CHEMBL194861)
Affinity DataKi:  3.10nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19769((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)
Affinity DataKi:  4.30nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002366(CHEMBL433985)
Affinity DataKi:  5nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002400(CHEMBL382286)
Affinity DataKi:  5.70nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19810(CHEMBL118449 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  8nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002398(CHEMBL196023)
Affinity DataKi:  8.20nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002367(CHEMBL407633)
Affinity DataKi:  8.90nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19815((2S)-2-(1-benzothiophen-2-ylformamido)-4-methyl-N-...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002367(CHEMBL407633)
Affinity DataKi:  11nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002400(CHEMBL382286)
Affinity DataKi:  12nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002402(CHEMBL194643)
Affinity DataKi:  16nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19810(CHEMBL118449 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  16nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002374(CHEMBL194861)
Affinity DataKi:  24nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002366(CHEMBL433985)
Affinity DataKi:  27nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19807(CHEMBL100563 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  39nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002398(CHEMBL196023)
Affinity DataKi:  41nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19804((2S)-4-methyl-N-(4-oxooxolan-3-yl)-2-(quinolin-2-y...)
Affinity DataKi:  44nM ΔG°:  -41.6kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19813(benzyl N-[(2S)-4-methyl-1-{3-[(2S)-4-methyl-2-(qui...)
Affinity DataKi:  46nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19809(benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl...)
Affinity DataKi:  49nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19809(benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl...)
Affinity DataKi:  51nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002398(CHEMBL196023)
Affinity DataKi:  52nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19797(CHEMBL301683 | acyclic alkoxymethyl ketone inhibit...)
Affinity DataKi:  60nM ΔG°:  -40.8kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19812([(2S)-1-{3-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-...)
Affinity DataKi:  77nM ΔG°:  -40.2kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19807(CHEMBL100563 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Affinity DataKi:  90nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002402(CHEMBL194643)
Affinity DataKi:  150nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19799(4-amidotetrahydropyran-3-one, 4 | benzyl N-[(1S)-3...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19809(benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50002367(CHEMBL407633)
Affinity DataKi:  193nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19806(benzyl N-[(1S)-1-[(1-acetyl-3-oxopiperidin-4-yl)ca...)
Affinity DataKi:  230nM ΔG°:  -37.5kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19804((2S)-4-methyl-N-(4-oxooxolan-3-yl)-2-(quinolin-2-y...)
Affinity DataKi:  250nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19805(benzyl N-[(1S)-1-[(1-acetyl-4-oxopyrrolidin-3-yl)c...)
Affinity DataKi:  250nM ΔG°:  -37.3kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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