Affinity DataKi: 2.70nMAssay Description:Inhibition of recombinant human BChE at 50 nM by stopped flow apparatus methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibition of human recombinant AKR1C1 assessed as 1-acenaphthenol oxidation at 400 uM by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of recombinant human BChE at 50 nM by stopped flow apparatus methodMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Competitive inhibition of human recombinant AKR1C3 assessed as S-tetralol oxidation by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 143nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of wild type human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human recombinant AKR1C3 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 585nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 585nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 810nMAssay Description:Inhibition of human recombinant AKR1C1 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 911nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of human recombinant AKR1C3 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 2.73E+3nMAssay Description:Competitive inhibition of human recombinant AKR1C3 assessed as S-tetralol oxidation by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of human recombinant AKR1C1 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of human recombinant AKR1C3 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Reversible inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 5.40E+3nMAssay Description:Reversible inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 5.96E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.96E+3nMAssay Description:Inhibition of human wild type carbonic anhydrase 2 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Reversible inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as substrate ...More data for this Ligand-Target Pair