Affinity DataIC50: 0.900nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-fused recombinant VGFR2 (unknown origin) catalytic domain expressed in baculovirus-infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-fused recombinant VGFR2 (unknown origin) catalytic domain expressed in baculovirus-infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of TPR-met autophosphorylation expressed in HEK293T cells after 150 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition against partially purified human histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair