Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]methyl-spiperone from human dopamine D2s receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Displacement of [3H]imipramine from human 5HT transporterMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I](+/-)-DOI from human 5HT2B receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]BTCP from human DA transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]nisoxetine from human NE transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]BRL43694 from human 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I]CYP from human 5HT1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli assessed as reduction in formation of N-formylkynurenine by measuring apparent inh...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H](-)-CGP12177 from human adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]LSD from human 5HT5A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Competitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 490...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of IDO by cell-free assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Uncompetitive inhibition of hexahistidyl-tagged human IDO1More data for this Ligand-Target Pair
Affinity DataKi: 3.24E+4nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Uncompetitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 4...More data for this Ligand-Target Pair
Affinity DataKi: 1.15E+7nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 7 hrs by UPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.4Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 7.4 after 60 mins by HPLC an...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 7 hrs by UPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 7 hrs by UPLC analysisMore data for this Ligand-Target Pair