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Found 33 with Last Name = 'vanwert' and Initial = 'al'
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50350467(BL-S578 | CEFADROXIL | Cefadrops)
Affinity DataKi:  8.62E+3nMAssay Description:Inhibition of human OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  95nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  122nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  289nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  289nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  319nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  367nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  433nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  462nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  480nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  788nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  2.99E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50: >7.20E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  7.54E+3nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50350476(BRL-1702 | DICLOXACILLIN)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM82898((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50103525(CHEBI:7447 | Nafcillin | Nallpen | Unipen)
Affinity DataIC50:  3.49E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50350483(Bactocill | OXACILLIN)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50103524(Ceftiofur)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50370584(Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...)
Affinity DataIC50:  4.86E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50335563((6R,7R)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-(...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  8.94E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50350471(CEFMETAZOLE)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50103523(CHEBI:6827 | Methicillin | Meticillin | Staphcilli...)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Wilkes University

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Mus musculus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50103522(BRL-2288 | CHEBI:9587 | Tarcil | Ticar | Ticarcill...)
Affinity DataIC50:  2.33E+5nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Wilkes University

Curated by ChEMBL
LigandPNGBDBM50350467(BL-S578 | CEFADROXIL | Cefadrops)
Affinity DataIC50:  1.78E+6nMAssay Description:Inhibition of rat OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed