Found 82 with Last Name = 'vaquero' and Initial = 'jj' 
Affinity DataKi: 2.83E+3nMAssay Description:Non competitive type inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human TC-PTP (2 to 315 residues) expressed in Escherichia coli using pNPP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universidad De Alcala
Curated by ChEMBL
Universidad De Alcala
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
