TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I at 10 uMMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.860nMpH: 7.5 T: 2°CAssay Description:Compounds were tested as inhibitors of FTase in vitro using purified human enzyme to catalyze the reaction between [3H] FPP and a biotinylated peptid...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair