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Found 15 with Last Name = 'vergauwen' and Initial = 'k'
TargetATP synthase subunit c(Mycobacterium smegmatis)
Tibotec

Curated by ChEMBL
LigandPNGBDBM50333125((1R,2S)-1-(6-bromoquinolin-3-yl)-4-(dimethylamino)...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Mycobacterium smegmatis ATCC 607 ATP synthase subunit c-mediated ATP synthesis after 60 mins by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit c(Mycobacterium smegmatis)
Tibotec

Curated by ChEMBL
LigandPNGBDBM50333125((1R,2S)-1-(6-bromoquinolin-3-yl)-4-(dimethylamino)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Mycobacterium smegmatis MC2 155 ATP synthase subunit c-mediated ATP production at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit c(Mycobacterium smegmatis)
Tibotec

Curated by ChEMBL
LigandPNGBDBM50333125((1R,2S)-1-(6-bromoquinolin-3-yl)-4-(dimethylamino)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Mycobacterium smegmatis MC2 155 ATP synthase subunit c-mediated ATP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit c(Mycobacterium smegmatis)
Tibotec

Curated by ChEMBL
LigandPNGBDBM50416574(CHEMBL1221824)
Affinity DataIC50:  25nMAssay Description:Inhibition of Mycobacterium smegmatis ATCC 607 ATP synthase subunit c-mediated ATP synthesis after 60 mins by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288737(CHEMBL4168125)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288739(CHEMBL4173963)
Affinity DataIC50:  230nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit c(Mycobacterium smegmatis)
Tibotec

Curated by ChEMBL
LigandPNGBDBM50416573(CHEMBL1221879)
Affinity DataIC50:  750nMAssay Description:Inhibition of Mycobacterium smegmatis ATCC 607 ATP synthase subunit c-mediated ATP synthesis after 60 mins by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed