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Found 30 with Last Name = 'vescovini' and Initial = 'k'
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  96nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.74E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  3.04E+3nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054321((7,9-Dimethyl-3-oxo-5,6-dihydro-3H-benzo[h]cinnoli...)
Affinity DataIC50:  6.44E+3nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054326(4-(8,9-Dimethoxy-3-oxo-5,6-dihydro-3H-benzo[h]cinn...)
Affinity DataIC50:  7.56E+3nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of Aldehyde reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054328(4-(3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-but...)
Affinity DataIC50:  1.14E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054332(3-Oxo-3,5-dihydro-2H-indeno[1,2-c]pyridazine-4-car...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054320((3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-aceti...)
Affinity DataIC50:  1.26E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054327(4-(7,9-Dimethyl-3-oxo-5,6-dihydro-3H-benzo[h]cinno...)
Affinity DataIC50:  1.74E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054331(3-Oxo-2,3,5,6-tetrahydro-benzo[h]cinnoline-4-carbo...)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054317((7,8-Dimethoxy-3-oxo-3,5-dihydro-indeno[1,2-c]pyri...)
Affinity DataIC50:  2.64E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054329(2-Carboxymethyl-3-oxo-2,3,5,6-tetrahydro-benzo[h]c...)
Affinity DataIC50:  3.30E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.99E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054319(3-(7,9-Dimethyl-3-oxo-5,6-dihydro-3H-benzo[h]cinno...)
Affinity DataIC50:  5.15E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054330((9-Methyl-3-oxo-4,4a,5,6-tetrahydro-3H-benzo[h]cin...)
Affinity DataIC50:  6.35E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054315((3-Oxo-3,5,6,7-tetrahydro-benzo[6,7]cyclohepta[1,2...)
Affinity DataIC50:  7.62E+4nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054328(4-(3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-but...)
Affinity DataIC50:  9.26E+4nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054324((3-Oxo-3,5-dihydro-indeno[1,2-c]pyridazin-2-yl)-ac...)
Affinity DataIC50:  1.07E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054325((8,9-Dimethoxy-3-oxo-5,6-dihydro-3H-benzo[h]cinnol...)
Affinity DataIC50:  1.14E+5nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054323(3-(3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-pro...)
Affinity DataIC50:  1.33E+5nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054316(2-Carboxymethyl-3-oxo-3,5-dihydro-2H-indeno[1,2-c]...)
Affinity DataIC50:  1.36E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054320((3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-aceti...)
Affinity DataIC50:  1.56E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054329(2-Carboxymethyl-3-oxo-2,3,5,6-tetrahydro-benzo[h]c...)
Affinity DataIC50:  1.61E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50054318(3-(8,9-Dimethoxy-3-oxo-5,6-dihydro-3H-benzo[h]cinn...)
Affinity DataIC50:  1.62E+5nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSorbitol dehydrogenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of sorbitol dehydrogenase from sheep liver (40 U/mg of protein)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  2.18E+5nMAssay Description:Inhibition of Glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054319(3-(7,9-Dimethyl-3-oxo-5,6-dihydro-3H-benzo[h]cinno...)
Affinity DataIC50:  2.89E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054321((7,9-Dimethyl-3-oxo-5,6-dihydro-3H-benzo[h]cinnoli...)
Affinity DataIC50:  2.95E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed