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Found 24 with Last Name = 'vicente' and Initial = 'f'
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50: <4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  8nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM24226(1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxypheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406470(Kibdelomycin)
Affinity DataIC50:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Pseudomonas aeruginosa DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
LigandPNGBDBM50613105(CHEMBL5271811)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
LigandPNGBDBM50613100(CHEMBL5275604)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM50613107(CHEMBL5267594)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613103(CHEMBL5269847)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613104(CHEMBL5268463)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613106(CHEMBL5276709)
Affinity DataIC50:  13nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613101(CHEMBL5282927)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613102(CHEMBL5285251)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50486087(Kibdelomycin A)
Affinity DataIC50:  400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha relaxationMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389213(CHEMBL2063169)
Affinity DataIC50: >2.27E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389212(CHEMBL2063168)
Affinity DataIC50: >2.34E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389211(CHEMBL2063167)
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed