Compile Data Set for Download or QSAR
maximum 50k data
Found 37 with Last Name = 'vidalain' and Initial = 'po'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50070908(CHEMBL3409491)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human purified recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50070905(CHEMBL3409286)
Affinity DataIC50:  13nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50070906(CHEMBL3409299)
Affinity DataIC50:  16nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50095120(CHEMBL3589752)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  40nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50070907(CHEMBL3409306)
Affinity DataIC50:  126nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  127nMAssay Description:Inhibition of rat recombinant His-tagged truncated DHODH expressed in Escherichia coli using dihydroorotate as substrate by chromogen reduction assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  367nMAssay Description:Inhibition of rat purified recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50203188(2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy...)
Affinity DataIC50:  700nMAssay Description:Inhibition of rat purified recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50203188(2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of human purified recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550731(CHEMBL4745158)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550732(CHEMBL4755999)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550733(CHEMBL4795021)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550734(CHEMBL4789182)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550735(CHEMBL4748394)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550736(CHEMBL4741980)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550730(CHEMBL4777624)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550729(CHEMBL4753543)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550728(CHEMBL4748412)
Affinity DataEC50:  5.25E+4nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataEC50:  8.91E+3nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataEC50:  2.75E+3nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50069959(Brequinar sodium | CHEMBL300058 | Sodium; 6-fluoro...)
Affinity DataEC50:  55nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataEC50:  8.90E+3nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550727(CHEMBL3128253)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550724(CHEMBL4750208)
Affinity DataEC50:  2.69E+4nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550723(CHEMBL4740037)
Affinity DataEC50:  4.47E+4nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550737(CHEMBL4743368)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550725(CHEMBL4790954)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550724(CHEMBL4750208)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550723(CHEMBL4740037)
Affinity DataEC50:  4.40E+4nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50550726(CHEMBL3128254)
Affinity DataEC50: <1.58E+5nMAssay Description:Inhibition of DHODH in human HEK-293 cells transfected with ISRE-luciferase reporter gene assessed as increase in IFN-alpha mediated cellular respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed