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Found 230 with Last Name = 'villoutreix' and Initial = 'b'
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50317441(ATWLPPR | CHEMBL1095672)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50047413(CHEMBL1624864)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50047414(CHEMBL3311013)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50047415(CHEMBL1621063)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50047412(CHEMBL3311014)
Affinity DataKi:  1.13E+4nMAssay Description:Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444601(CHEMBL3099881)
Affinity DataKi:  1.50E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444601(CHEMBL3099881)
Affinity DataKi:  4.40E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444600(CHEMBL1462676)
Affinity DataKi:  5.00E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444598(CHEMBL3099878)
Affinity DataKi:  5.50E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444604(CHEMBL3099870)
Affinity DataKi:  7.00E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444602(CHEMBL3099874)
Affinity DataKi:  7.20E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444603(CHEMBL3099871)
Affinity DataKi:  7.50E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444597(CHEMBL3099882)
Affinity DataKi:  8.30E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444597(CHEMBL3099882)
Affinity DataKi:  9.50E+4nMAssay Description:Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444599(CHEMBL3099875)
Affinity DataKi:  9.50E+4nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-inhibitor complex after 15 to 60 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444602(CHEMBL3099874)
Affinity DataKi:  1.00E+5nMAssay Description:Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444603(CHEMBL3099871)
Affinity DataKi:  1.07E+5nMAssay Description:Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444604(CHEMBL3099870)
Affinity DataKi:  1.12E+5nMAssay Description:Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444598(CHEMBL3099878)
Affinity DataKi:  1.21E+5nMAssay Description:Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444604(CHEMBL3099870)
Affinity DataKi:  1.29E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444598(CHEMBL3099878)
Affinity DataKi:  1.31E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444599(CHEMBL3099875)
Affinity DataKi:  1.40E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444603(CHEMBL3099871)
Affinity DataKi:  1.52E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444602(CHEMBL3099874)
Affinity DataKi:  1.64E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444600(CHEMBL1462676)
Affinity DataKi:  1.66E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444597(CHEMBL3099882)
Affinity DataKi:  1.66E+5nMAssay Description:Mixed-type inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate assessed as enzyme-substrate-inhibitor complex after 15 to 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441574(CHEMBL2437163)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441587(CHEMBL2437157)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441598(CHEMBL2437156)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441592(CHEMBL2437170)
Affinity DataIC50:  490nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441590(CHEMBL2437164)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441590(CHEMBL2437164)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant ADAMTS-4 using QTVTWPDMELPLPRNITEGEARGSVIL-TVKPIFEVSPSPL(biotinyl)K as substrate incubated for 10 mins prior to subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441574(CHEMBL2437163)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant ADAMTS-4 using QTVTWPDMELPLPRNITEGEARGSVIL-TVKPIFEVSPSPL(biotinyl)K as substrate incubated for 10 mins prior to subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441586(CHEMBL2437153)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441593(CHEMBL2437173)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441587(CHEMBL2437157)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant ADAMTS-4 using QTVTWPDMELPLPRNITEGEARGSVIL-TVKPIFEVSPSPL(biotinyl)K as substrate incubated for 10 mins prior to subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441589(CHEMBL2437160)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant ADAMTS-4 using QTVTWPDMELPLPRNITEGEARGSVIL-TVKPIFEVSPSPL(biotinyl)K as substrate incubated for 10 mins prior to subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441589(CHEMBL2437160)
Affinity DataIC50:  810nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50441588(CHEMBL2437159)
Affinity DataIC50:  880nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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