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Found 41 with Last Name = 'viola' and Initial = 'a'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498365(CHEMBL3590531)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human alpha4beta1integrin in human Jurkat cells assessed as reduction of VCAM-1-induced ERK1/2 phosphorylation after 60 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498365(CHEMBL3590531)
Affinity DataIC50:  10nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439689(CHEMBL2418214)
Affinity DataIC50:  19nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222359(2-{[1-(4-aminobutyl)-4-methyl-2-oxo-6-phenyl-1,2,5...)
Affinity DataIC50:  38nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222359(2-{[1-(4-aminobutyl)-4-methyl-2-oxo-6-phenyl-1,2,5...)
Affinity DataIC50:  43nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  62nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222357(3-(((R)-1-((S)-1-(4-aminophenyl)ethyl)-4-methyl-2-...)
Affinity DataIC50:  71nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498362(CHEMBL3590528)
Affinity DataIC50:  110nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439687(CHEMBL2418217)
Affinity DataIC50:  120nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  131nMAssay Description:Antagonist activity at human alpha4beta1integrin in human Jurkat cells assessed as reduction of VCAM-1-induced ERK1/2 phosphorylation after 60 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439684(CHEMBL2418220)
Affinity DataIC50:  170nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222361(2-({1-[(4-aminophenyl)methyl]-4-methyl-2-oxo-6-phe...)
Affinity DataIC50:  170nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439686(CHEMBL2418218)
Affinity DataIC50:  220nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439682(CHEMBL2418222)
Affinity DataIC50:  230nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498366(CHEMBL3590529)
Affinity DataIC50:  250nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439684(CHEMBL2418220)
Affinity DataIC50:  270nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498365(CHEMBL3590531)
Affinity DataIC50:  270nMAssay Description:Inhibition of human alpha4beta7 integrin expressed in human RPMI8866 cells assessed as inhibition of cell adhesion to MadCam1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  343nMAssay Description:Inhibition of human alpha4beta7 integrin expressed in human RPMI8866 cells assessed as inhibition of cell adhesion to MadCam1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50222361(2-({1-[(4-aminophenyl)methyl]-4-methyl-2-oxo-6-phe...)
Affinity DataIC50:  600nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439688(CHEMBL2418216)
Affinity DataIC50:  830nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50:  930nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498363(CHEMBL3590532)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta1 integrin expressed in human K-562 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498365(CHEMBL3590531)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta3 integrin expressed in human SK-MEL-24 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta3 integrin expressed in human SK-MEL-24 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498361(CHEMBL3590530)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498365(CHEMBL3590531)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta1 integrin expressed in human K-562 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439691(CHEMBL2418224)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439690(CHEMBL2418215)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439686(CHEMBL2418218)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439688(CHEMBL2418216)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439691(CHEMBL2418224)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439690(CHEMBL2418215)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439687(CHEMBL2418217)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439682(CHEMBL2418222)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439685(CHEMBL2418219)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439685(CHEMBL2418219)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50439689(CHEMBL2418214)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed