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Found 218 with Last Name = 'viola' and Initial = 'g'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50442742(CHEMBL2442999)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50442743(CHEMBL2442998)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50442744(CHEMBL2442997)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604641(CHEMBL5183674)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442322(CHEMBL2442760)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563723(CHEMBL4128865)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of wild-type human CK1delta using PLSRTLpSVASLPGL as substrate incubated for 40 mins in presence of ATP by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442326(CHEMBL2442758)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604641(CHEMBL5183674)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442323(CHEMBL2442759)
Affinity DataIC50:  6nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604642(CHEMBL5206333)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of full-length human CK1epsilon expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cells using PLSRTLpSVASLPGL as substrate i...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50:  10nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442325(CHEMBL2442756)
Affinity DataIC50:  11nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442320(CHEMBL2442762)
Affinity DataIC50:  13nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  14nMAssay Description:Inhibition of full-length human CK1delta expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cells using PLSRTLpSVASLPGL as substrate inc...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604642(CHEMBL5206333)
Affinity DataIC50:  14nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563723(CHEMBL4128865)
Affinity DataIC50:  17nMAssay Description:Inhibition of wild-type human CK1epsilon using PLSRTLpSVASLPGL as substrate incubated for 70 mins in presence of ATP by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50:  23nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517545(CHEMBL4546122)
Affinity DataIC50:  52nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442323(CHEMBL2442759)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP11B1 using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563717(CHEMBL4742954)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CK1delta (1 to 294 residues) using casein as substrate measured after 60 mins in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563710(CHEMBL4793727)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CK1delta (1 to 294 residues) using casein as substrate measured after 60 mins in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442325(CHEMBL2442756)
Affinity DataIC50:  230nMAssay Description:Inhibition of human CYP11B1 using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442326(CHEMBL2442758)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CYP11B1 using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517544(CHEMBL4552482)
Affinity DataIC50:  273nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563717(CHEMBL4742954)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CK1delta using casein as substrate measured after 10 mins in presence of ATP by Kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563711(CHEMBL4793501)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CK1delta (1 to 294 residues) using casein as substrate measured after 60 mins in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528631(CHEMBL4526719)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50563706(CHEMBL4776464)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CK1delta (1 to 294 residues) using casein as substrate measured after 60 mins in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517543(CHEMBL4572443)
Affinity DataIC50:  326nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528630(CHEMBL4440494)
Affinity DataIC50:  340nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528642(CHEMBL4447541)
Affinity DataIC50:  350nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528635(CHEMBL4473254)
Affinity DataIC50:  360nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528638(CHEMBL4442113)
Affinity DataIC50:  370nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528629(CHEMBL4524533)
Affinity DataIC50:  370nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50508919(CHEMBL4459174)
Affinity DataIC50:  380nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528636(CHEMBL4464909)
Affinity DataIC50:  390nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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