Compile Data Set for Download or QSAR
maximum 50k data
Found 14 with Last Name = 'vollmar' and Initial = 'm'
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University of Munich

LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  1.50E+3nMpH: 7.5 T: 2°CAssay Description:PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin, alpha skeletal muscle(Oryctolagus cuniculus)
Ludwig-Maximilians-University

Curated by ChEMBL
LigandPNGBDBM50508923(CHEBI:49703 | LATRUNCULIN B | NSC-339663)
Affinity DataIC50:  8.47E+3nMAssay Description:Inhibition of rabbit skeletal muscle alpha-actin polymerization measured after 24 hrs in presence of ATP and fluorescent pyrene-labelled actin by flu...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50334671(CHEMBL1642586 | kaempferol-3-O-alpha-L-(2'', 4''-d...)
Affinity DataIC50: >1.04E+4nMAssay Description:Displacement of fluorescent SM5F peptide from XIAP linker BIR3 domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin, alpha skeletal muscle(Oryctolagus cuniculus)
Ludwig-Maximilians-University

Curated by ChEMBL
LigandPNGBDBM50508924(CHEMBL4522174)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of rabbit skeletal muscle alpha-actin polymerization measured after 24 hrs in presence of ATP and fluorescent pyrene-labelled actin by flu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University of Munich

LigandPNGBDBM81296(5BIO)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University of Munich

LigandPNGBDBM50218894(7-bromoindirubin-3-oxime | 7BIO | CHEMBL1092509)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50213414(CHEMBL240528 | afzelin | kaempferol 3-O-alpha-L-rh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent SM5F peptide from XIAP linker BIR3 domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent SM5F peptide from XIAP linker BIR3 domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University of Munich

LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone demethylase UTY [818-1347,S1138G](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  1.15E+5nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone demethylase UTY [818-1347,P1214I](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  800nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone demethylase UTY [818-1347](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  7.80E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed