Compile Data Set for Download or QSAR
maximum 50k data
Found 16 with Last Name = 'von hoff' and Initial = 'dd'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153810((S)-11-Benzyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-...)
Affinity DataEC50:  4.56E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153814(7-ethyl-7-hydroxy-14-(4-methylphenyl)-(7S)-7,8,11,...)
Affinity DataEC50:  1.16E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataEC50:  350nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153815(14-cyclohexyl-7-ethyl-7-hydroxy-(7S)-7,8,11,13-tet...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153808((S)-11-tert-Butyl-4-ethyl-4-hydroxy-1,12-dihydro-4...)
Affinity DataEC50:  240nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153817(7-ethyl-7-hydroxy-14-phenyl-(7S)-7,8,11,13-tetrahy...)
Affinity DataEC50:  150nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153818(7-ethyl-7-hydroxy-14-(4-methylphenyl)-(7S)-7,8,11,...)
Affinity DataEC50:  1.04E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153807((S)-4-Ethyl-4-hydroxy-11-isobutyl-1,12-dihydro-4H-...)
Affinity DataEC50:  450nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153816(14-benzyl-7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahy...)
Affinity DataEC50:  1.95E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50092821((R)-4-Ethyl-4-methyl-1,4a,12,13a-tetrahydro-4H-2-o...)
Affinity DataEC50:  320nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153809(7-ethyl-7-hydroxy-14-(4-trifluoromethylphenyl)-(7S...)
Affinity DataEC50:  160nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153813(7-ethyl-14-(4-fluorophenyl)-7-hydroxy-(7S)-7,8,11,...)
Affinity DataEC50:  1.39E+3nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50036133(7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-10H-[1...)
Affinity DataEC50:  50nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153819((S)-11-Butyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-o...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153811(14-cyclopentyl-7-ethyl-7-hydroxy-(7S)-7,8,11,13-te...)
Affinity DataEC50:  190nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153812(7,14-diethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-1...)
Affinity DataEC50:  270nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed