TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
National Institutes of Health
National Institutes of Health
Affinity DataIC50: 67nMAssay Description:The compound were evaluated in biochemical IN (integrase) assay that measure inhibitory potency (IC50 values)against both the 3'-processing(3'...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 60 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 60 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase-mediated viral DNA synthesis in human HOS-313 cells expressing HSV thymidine kinase assessed as lu...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of HIV1 reverse transcriptase M184V mutant-mediated viral DNA synthesis in human HOS-313 cells expressing HSV thymidine kinase assessed as...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase-mediated viral DNA synthesis in human HOS cells assessed as luciferase activity treated 3 hrs befo...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of manganeseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase-mediated viral DNA synthesis in human HOS-313 cells expressing HSV thymidine kinase assessed as lu...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 60 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair