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Found 106 with Last Name = 'wágner' and Initial = 'g'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323373(1,2-dicyclohexyl-3-(pyridin-3-yl)propan-1-one O-3-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM86716(CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...)
Affinity DataKi:  6.70nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM86716(CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...)
Affinity DataKi:  6.76nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323380((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323371((+)-1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-...)
Affinity DataKi:  8.78nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323378((3-chlorophenylamino)(1,2-dicyclohexyl-3-(6-thioxo...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397487(US9994525, Example 3)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397490(US9994525, Example 5)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397495(US9994525, Example 10)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397497(US9994525, Example 12)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397498(US9994525, Example 13)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397499(US9994525, Example 14)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397500(US9994525, Example 15)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397501(US9994525, Example 16)
Affinity DataKi: <10nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323379((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323377((3-chlorophenylamino)(1,2-dicyclohexyl-3-(5-thioxo...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323375(CHEMBL1209400 | c1,2-dicyclohexyl-3-(1H-pyrrol-3-y...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323365(1,2-dicyclohexyl-3-phenylpropan-1-one O-3-chloroph...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397493(US9994525, Example 8)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397494(US9994525, Example 9)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397496(US9994525, Example 11)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397475(US9994525, Example 1)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397476(US9994525, Example 2)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397489(US9994525, Example 4)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323363(1,2-dicyclohexyl-3-phenylpropan-1-one O-m-tolylcar...)
Affinity DataKi:  30nMAssay Description:Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397491(US9994525, Example 6)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Richter Gedeon

US Patent
LigandPNGBDBM397492(US9994525, Example 7)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in at least 5 concentrations, with two parallel samples in each concentrations, in at least two independent ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323370(1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-one ...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)
Affinity DataKi:  36nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)
Affinity DataKi:  36.3nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323369(3-((1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propylide...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323374(1,2-dicyclohexyl-3-(pyridin-2-yl)propan-1-one O-3-...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323366(1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323372(1,2-dicyclohexyl-3-(4-methyl-1H-imidazol-1-yl)prop...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416269(CHEMBL1082329)
Affinity DataKi:  49.0nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323364(1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416264(CHEMBL1082987)
Affinity DataKi:  57.5nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416276(CHEMBL1082975)
Affinity DataKi:  72.4nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416263(CHEMBL1086591)
Affinity DataKi:  77.6nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323368(1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-one ...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416265(CHEMBL1083340)
Affinity DataKi:  83.2nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416270(CHEMBL1082976)
Affinity DataKi:  87.1nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323381((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416260(CHEMBL1083598)
Affinity DataKi:  89.1nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416271(CHEMBL1084474)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323382((E)-2-((1H-imidazol-1-yl)methyl)cyclohexanone O-ph...)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416272(CHEMBL1084475)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323387(1,2-dicyclohexyl-3-(pyridin-4-yl)propan-1-one O-3-...)
Affinity DataKi:  117nMAssay Description:Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416275(CHEMBL1083341)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50416279(CHEMBL1084476)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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