Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Bacillus subtilis histidine kinase YycGMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.53E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.35E+4nMAssay Description:Inhibition of Bacillus subtilis histidine kinase YycGMore data for this Ligand-Target Pair
Affinity DataIC50: 6.45E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 6.65E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Osaka University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 8.32E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 8.92E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.91E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair