Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 1.20nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 2nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 2nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 3nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 3nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 3.40nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Aska Pharmaceutical
US Patent
Aska Pharmaceutical
US Patent
Affinity DataIC50: 10nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
Affinity DataIC50: 10.9nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14.7nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20.1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair