Affinity DataKi: 7nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using midazolam as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using nifedipine as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using testosterone as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using midazolam as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.87E+5nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using testosterone as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.03E+5nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes using nifedipine as a substrate by LC/MS analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human epidermal growth factor receptor-2More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of CYP3A4 activity in human liver microsomes assessed as dibenzo fluuorescene oxidation up to 40 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 235nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
Affinity DataEC50: 0.0950nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.5nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.10nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.80nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assayMore data for this Ligand-Target Pair