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Found 85 with Last Name = 'wang' and Initial = 'ly'
TargetCathepsin E(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataKi:  5nMAssay Description:Binding affinity to human cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataKi:  24nMAssay Description:Binding affinity to human cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataKi:  36nMAssay Description:Binding affinity to human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataKi:  291nMAssay Description:Binding affinity to human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291962(CHEMBL4174080)
Affinity DataKi:  2.34E+3nMAssay Description:Competitive inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
National Tsing Hua University

Curated by ChEMBL
LigandPNGBDBM50047962(CHEMBL1966136)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of recombinant human KDM4B (1 to 348 aa) expressed in Escherichia coli using H3K9me3 peptide as substrate after 30 mins by dou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
National Tsing Hua University

Curated by ChEMBL
LigandPNGBDBM50047962(CHEMBL1966136)
Affinity DataKi:  5.50E+3nMAssay Description:Competitive inhibition of recombinant human KDM4A (1 to 347 aa) expressed in Escherichia coli using H3K9me3 peptide as substrate after 30 mins by dou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataIC50:  3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372186(CHEMBL257645)
Affinity DataIC50:  4nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataIC50:  5nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372187(CHEMBL404078)
Affinity DataIC50:  6nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372189(CHEMBL399979)
Affinity DataIC50:  7nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372184(CHEMBL402276)
Affinity DataIC50:  12nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227345(CHEMBL255194 | N'-[(1S,2R)-2-[(2R,4S)-4-benzylpipe...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372185(CHEMBL256372)
Affinity DataIC50:  26nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataIC50:  45nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataIC50:  54nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372200(CHEMBL256434)
Affinity DataIC50:  65nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372197(CHEMBL258083)
Affinity DataIC50:  70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372182(CHEMBL404680)
Affinity DataIC50:  89nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372186(CHEMBL257645)
Affinity DataIC50:  110nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372188(CHEMBL401527)
Affinity DataIC50:  120nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372187(CHEMBL404078)
Affinity DataIC50:  121nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227347(CHEMBL270153 | N1-((1R,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataIC50:  150nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372189(CHEMBL399979)
Affinity DataIC50:  160nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataIC50:  165nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372199(CHEMBL255372)
Affinity DataIC50:  187nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372193(CHEMBL256904)
Affinity DataIC50:  191nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CE1 using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  210nMAssay Description:Inhibition of CE1 in human liver microsomes using D-Luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227347(CHEMBL270153 | N1-((1R,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372195(CHEMBL257907)
Affinity DataIC50:  330nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372200(CHEMBL256434)
Affinity DataIC50:  330nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372194(CHEMBL428074)
Affinity DataIC50:  440nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372185(CHEMBL256372)
Affinity DataIC50:  482nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227345(CHEMBL255194 | N'-[(1S,2R)-2-[(2R,4S)-4-benzylpipe...)
Affinity DataIC50:  522nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372184(CHEMBL402276)
Affinity DataIC50:  567nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372192(CHEMBL257091)
Affinity DataIC50:  610nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372191(CHEMBL257087)
Affinity DataIC50:  630nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372183(CHEMBL272320)
Affinity DataIC50:  770nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372199(CHEMBL255372)
Affinity DataIC50:  780nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372188(CHEMBL401527)
Affinity DataIC50:  858nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372197(CHEMBL258083)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372196(CHEMBL257735)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372182(CHEMBL404680)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372193(CHEMBL256904)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372190(CHEMBL256676)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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