Compile Data Set for Download or QSAR
maximum 50k data
Found 3337 with Last Name = 'ward' and Initial = 'n'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418229(CHEMBL1760646)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418228(CHEMBL1760645)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.933nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418210(CHEMBL1760664)
Affinity DataKi:  4.37nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418212(CHEMBL1760663)
Affinity DataKi:  5.01nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418213(CHEMBL1760661)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418211(CHEMBL1760662)
Affinity DataKi:  7.59nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077147(CHEMBL3416846)
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50343829((S)-1-(4-Dodecylbenzoyl)pyrrolidine-2-carboximidam...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-Amino-5-bromo-1H-pyrimidine-2,4-dione | 6-Amino-...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  851nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077146(CHEMBL3416840)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077143(CHEMBL3416833)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443388(CHEMBL3086782 | US9688668, SLR080811)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443388(CHEMBL3086782 | US9688668, SLR080811)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50343829((S)-1-(4-Dodecylbenzoyl)pyrrolidine-2-carboximidam...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077145(CHEMBL3416836)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50017016(CHEMBL3287036)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50017016(CHEMBL3287036)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077147(CHEMBL3416846)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077144(CHEMBL3416835)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077144(CHEMBL3416835)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418228(CHEMBL1760645)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077143(CHEMBL3416833)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077146(CHEMBL3416840)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077145(CHEMBL3416836)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418210(CHEMBL1760664)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418229(CHEMBL1760646)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443388(CHEMBL3086782 | US9688668, SLR080811)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443388(CHEMBL3086782 | US9688668, SLR080811)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50077148(CHEMBL3416760)
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataKi:  7.30E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataKi:  1.23E+7nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418222(CHEMBL1760652)
Affinity DataIC50:  0.513nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418221(CHEMBL1760653)
Affinity DataIC50:  0.575nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418220(CHEMBL1760654)
Affinity DataIC50:  0.631nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418223(CHEMBL1760651)
Affinity DataIC50:  0.759nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418224(CHEMBL1760650)
Affinity DataIC50:  0.776nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataIC50:  1nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418229(CHEMBL1760646)
Affinity DataIC50:  1.17nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50418217(CHEMBL1760657)
Affinity DataIC50:  1.32nMAssay Description:Antagonist activity against human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astex

LigandPNGBDBM12588((2R,3S)-3-({[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)...)
Affinity DataIC50:  1.40nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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