Compile Data Set for Download or QSAR
maximum 50k data
Found 30 with Last Name = 'warnault' and Initial = 'p'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  6nMAssay Description:Inhibition of His-tagged full length human recombinant wild type ABL expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length GST-tagged human recombinant BRAF V600E mutant expressed in baculovirus using Fluorescein-MAP2K1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  15nMAssay Description:Inhibition of GST-tagged human recombinant EGFR (668 to1210 residues) expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-tagged full length human recombinant HCK expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  37nMAssay Description:Inhibition of GST-tagged full length human recombinant LYNA expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  40nMAssay Description:Inhibition of full length His-tagged human recombinant cSRC expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  44nMAssay Description:Inhibition of GST-tagged full length human recombinant YES expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  46nMAssay Description:Inhibition of His-tagged full length human recombinant ABL G250E mutant expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  50nMAssay Description:Inhibition of full length GST-tagged human recombinant PDGFRalpha expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  51nMAssay Description:Inhibition of His-tagged full length human recombinant ABL Y253F mutant expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  62nMAssay Description:Inhibition of GST-tagged full length human recombinant FRK expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  69nMAssay Description:Inhibition of His-tagged full length human recombinant LCK expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  73nMAssay Description:Inhibition of His-tagged full length human recombinant ABL E255K mutant expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  112nMAssay Description:Inhibition of GST-tagged human recombinant EGFR T790M mutant (668 to 1210 residues) expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataIC50:  131nMAssay Description:Inhibition of His-tagged full length human recombinant FYN expressed in baculovirus using Fluorescein-Poly GT as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50020522(1-(((4-carbamoylpyridinium-1-yl)methoxy)methyl)-2-...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586078(CHEMBL5084128)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50239371(Atnaa | CHEBI:8354 | Duodote | Pralidoxime)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586080(CHEMBL5088176)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50333779(1,3-Bis(4-(Hydroxyimino-methyl)-pyridinium)-2-oxap...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586079(CHEMBL5069796)
Affinity DataIC50:  1.60E+6nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of human BCR-ABL T315I mutant expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of human BCR-ABL T315I mutant expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of human BCR-ABL T315I mutant expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of human BCR-ABL T315I mutant expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataEC50:  1.80nMAssay Description:Inhibition of human BCR-ABL T315I mutant expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataEC50:  34nMAssay Description:Inhibition of human wild type BCR-ABL expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataEC50:  0.0500nMAssay Description:Inhibition of human wild type BCR-ABL expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50172492(CHEMBL3808884)
Affinity DataEC50:  0.0400nMAssay Description:Inhibition of human wild type BCR-ABL expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataEC50:  0.0400nMAssay Description:Inhibition of human wild type BCR-ABL expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair