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Found 132 with Last Name = 'wecksler' and Initial = 'at'
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California

Curated by ChEMBL
LigandPNGBDBM50304296(CHEMBL594396 | Oleyl sulfate)
Affinity DataKi:  700nMAssay Description:Binding affinity to soybean LO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California

Curated by ChEMBL
LigandPNGBDBM50150484((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity to soybean LO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California

Curated by ChEMBL
LigandPNGBDBM50304295(CHEMBL611951 | Palmitoleyl sulfate)
Affinity DataKi:  1.40E+5nMAssay Description:Binding affinity to allosteric site of soybean LO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436443(CHEMBL2397141)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436442(CHEMBL2397142)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436441(CHEMBL2397143 | US9029401, 2575)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436438(CHEMBL2397146 | US9029401, 2316)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436437(CHEMBL2397147)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436436(CHEMBL2397140)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436435(CHEMBL2397139 | US9029401, 2225)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436434(CHEMBL2397138)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436433(CHEMBL2397137)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436432(CHEMBL2397136 | US9029401, 2287)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436431(CHEMBL2397149 | US9029401, 2576)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342211(4-(5-Phenyl-3-{3-[3-(4-trifluoromethoxy-phenyl)-ur...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342208(4-{3-[3-(3-Cycloheptyl-ureido)-propyl]-5-phenyl-py...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342207(4-{3-[3-(3-Adamantan-1-yl-ureido)-propyl]-5-phenyl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158500(US9029401, 2581)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158499(US9029401, 2580)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158498(US9029401, 2579)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158497(US9029401, 2578)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158496(US9029401, 2577)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158484(US9029401, 2221)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436435(CHEMBL2397139 | US9029401, 2225)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158485(US10383835, Compound 2228 | US9029401, 2227)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158486(US9029401, 2228)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158487(US10383835, Compound 2226 | US9029401, 2253)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158488(US9029401, 2278 (t-CUPM))
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436432(CHEMBL2397136 | US9029401, 2287)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158491(US9029401, 2315)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436438(CHEMBL2397146 | US9029401, 2316)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158492(US9029401, 2318)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158493(US9029401, 2319 (c-CUPM))
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158495(US9029401, 2574)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436441(CHEMBL2397143 | US9029401, 2575)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436431(CHEMBL2397149 | US9029401, 2576)
Affinity DataIC50:  0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158480(US9029401, 1686)
Affinity DataIC50:  0.600nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342209(4-(3-{3-[3-(4-Chloro-phenyl)-ureido]-propyl}-5-phe...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342206(4-{5-Phenyl-3-[3-(3-phenyl-ureido)-propyl]-pyrazol...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158494(US9029401, 2372)
Affinity DataIC50:  0.900nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342210(4-(5-Phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50:  0.900nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM158489(US9029401, 2280)
Affinity DataIC50:  0.900nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM25741(4-{[4-({[4-(trifluoromethoxy)phenyl]carbamoyl}amin...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436439(CHEMBL2397145)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50:  1.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342193(1-Cycloheptyl-3-[1-(4-methanesulfonyl-phenyl)-5-ph...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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