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Found 14 with Last Name = 'weinbaum' and Initial = 'c'
LigandPNGBDBM14713(GGTI-DU40 | N-[(1S)-1-carbamoyl-2-phenylethyl]-4-{...)
Affinity DataIC50:  8.24nMpH: 7.7 T: 2°CAssay Description:Compounds were tested as inhibitors of FTase or GGTase-1 in vitro using purified recombinant mammalian enzymes to catalyze the reactions between [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090637((2Z,6E)-7,11-dimethyl-3-(prop-1-en-2-yl)dodeca-2,6...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081229(10-(tert-butyl)-2,6-dimethyl-(6E,10Z)-2,6,10-dodec...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090639((2Z,6E)-7,11-dimethyl-3-(propan-2-yl)dodeca-2,6,10...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100979(Phosphoric acid di-((2Z,6E,10E)-3,7,11,15-tetramet...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]-GR-65,630 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090636((2Z,6E)-3-(butan-2-yl)-7,11-dimethyldodeca-2,6,10-...)
Affinity DataIC50:  102nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081235(3-substituted farnesyl diphosphate analogue | 4-[(...)
Affinity DataIC50:  119nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  173nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090642((2Z,6E)-7,11-dimethyl-3-(2-methylpropyl)dodeca-2,6...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100978(Phosphoric acid di-((2E,6Z,10E)-3,7,11,15-tetramet...)
Affinity DataIC50:  340nMAssay Description:Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]-GR-65,630 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090638((2E,6E)-7,11-dimethyl-3-propyldodeca-2,6,10-trien-...)
Affinity DataIC50:  453nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14713(GGTI-DU40 | N-[(1S)-1-carbamoyl-2-phenylethyl]-4-{...)
Affinity DataIC50: >2.00E+3nMpH: 7.7 T: 2°CAssay Description:Compounds were tested as inhibitors of FTase or GGTase-1 in vitro using purified recombinant mammalian enzymes to catalyze the reactions between [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090641((2Z,6E)-3-(2,2-dimethylpropyl)-7,11-dimethyldodeca...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50090640(3-substituted farnesyl diphosphate analogue | {[(2...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed