Affinity DataIC50: 8nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant CYP2C19 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant CYP2C19 coexpressed in Escherichia coliMore data for this Ligand-Target Pair