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Found 9 with Last Name = 'wendeler' and Initial = 'm'
TargetReverse transcriptase(Human immunodeficiency virus 2)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM33411(β-Thujaplicinol | hydroxytropolone, 3)
Affinity DataIC50:  250nMAssay Description:Inhibition of RNase H activity of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  2.00E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [613-1167,R896S,E946D,S1117V]/[618-1043,R896S,E946D](Human immunodeficiency virus type 2)
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  2.50E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  3.20E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [613-1167,R896S,E946D,S1117V]/[618-1043,R896S,E946D](Human immunodeficiency virus type 2)
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  1.06E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  2.90E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease HI(Escherichia coli (strain K12))
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  7.30E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease HI(Escherichia coli (strain K12))
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  1.00E+5nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed